5-Amino-1MQ is a synthetic small-molecule compound developed for laboratory research focused on metabolic regulation and adipose tissue signaling pathways. It has gained research interest due to its role as a nicotinamide N-methyltransferase (NNMT) inhibitor, a pathway associated with cellular energy balance and metabolic efficiency. 5-Amino-1MQ is formulated in capsule form strictly for controlled research applications.
Prior to the development and study of NNMT-targeted compounds like 5-Amino-1MQ, metabolic research largely relied on broad appetite suppressants or indirect metabolic modulators. Preclinical research has demonstrated that inhibition of NNMT may influence energy expenditure, fat metabolism, and cellular NAD⁺ availability, making 5-Amino-1MQ a notable subject in metabolic and obesity-related research models.
Currently, 5-Amino-1MQ is being investigated for its potential role in studies involving metabolic health, adiposity regulation, weight management models, and insulin sensitivity pathways. Additional research is exploring its influence on lipid metabolism, energy utilization, and cellular signaling involved in metabolic disorders. As research continues, 5-Amino-1MQ remains a compelling compound for ongoing laboratory investigation into targeted metabolic modulation.
5-Amino-1MQ is a research compound commonly discussed in laboratory contexts for its relationship to nicotinamide N-methyltransferase (NNMT) signaling and downstream metabolic pathway investigation. In preclinical literature, NNMT has been explored for its role in methylation balance, cellular energy regulation, and adipose tissue metabolism, positioning 5-Amino-1MQ as a tool compound for researchers studying how nicotinamide processing intersects with broader metabolic networks.
These capsules are supplied for controlled laboratory research only. Each batch is accompanied by lot-level documentation to support traceability, protocol documentation, and internal quality processes.
5-Amino-1MQ Research Capsule Specifications:
| Format | Capsules |
| Unit Quantity | See product label / lot documentation |
| Purity / Identity | Research-grade; refer to COA for lot-specific results |
| Active Compound | 5-Amino-1MQ (NNMT-pathway research compound) |
| Appearance | Encapsulated powder |
| Source | Chemical synthesis |
| Storage Conditions | Store sealed in a cool, dry environment, protected from heat, light, and humidity. Maintain lot integrity and documentation as required by internal lab SOPs. |
| Research Use Only | This product is supplied exclusively for laboratory research use. Not for human consumption, clinical use, or veterinary applications. Please review all terms and conditions prior to purchase. |
NNMT is an enzyme that methylates nicotinamide, influencing how nicotinamide is partitioned across methylation and energy-related pathways. Because nicotinamide is connected to NAD-related biology, NNMT research often overlaps with broader discussions about mitochondrial function, cellular energy handling, and metabolic phenotype signaling.
In research settings, 5-Amino-1MQ is referenced as a small-molecule tool used to probe NNMT-associated effects in adipose and metabolic models. Investigators may evaluate changes in energy expenditure readouts, adipocyte biology markers, and methylation-linked signaling outcomes, depending on the model and study design.
For teams building multi-pathway metabolic research programs, 5-Amino-1MQ is often discussed alongside cellular energy and mitochondrial pathway tools such as NAD and metabolic research peptides that support adipose and body-composition endpoints (for example, AOD-9604, Frag 176-191, Semaglutide, and Retatrutide)—not as consumer guidance, but as a protocol-planning lens for mapping pathway complementarity.
Important Research Notice: Nordsci products are supported by lot-level documentation. A Certificate of Analysis (COA) is available to support quality management, method alignment, and internal documentation requirements.
THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE OR CONDITION.
5-Amino-1MQ is frequently positioned as a tool compound for studying NNMT-linked metabolic signaling. In adipose-focused models, researchers may track downstream readouts tied to lipid handling, adipocyte behavior, and energy balance markers to evaluate how NNMT modulation aligns with measurable metabolic phenotype changes.
NNMT research often intersects with methylation biology because nicotinamide methylation can influence availability of methyl donors and related signaling dynamics. In these protocols, investigators may monitor methylation-adjacent biomarkers and pathway indicators while mapping how nicotinamide processing behaves under different metabolic conditions.
Because NNMT sits near nicotinamide biology, studies sometimes place 5-Amino-1MQ within a broader cellular energy context. Researchers may compare or contextualize findings against NAD-related frameworks using NAD and mitochondrial pathway probes such as MOTS-C to explore whether observed shifts appear more energy-driven, methylation-driven, or tissue-specific.
In advanced experimental design, 5-Amino-1MQ may be included as one component within a wider metabolic research framework. In these cases, teams typically define whether the primary endpoint is adipose biology, cellular energy handling, appetite/GLP-1 pathway signaling, or endocrine markers—and then select complementary tools accordingly (e.g., Semaglutide or Retatrutide for GLP-related literature alignment, and AOD-9604 or Frag 176-191 for adipose pathway models).
As a capsule-format research product, 5-Amino-1MQ is generally handled as a labeled, lot-tracked input for controlled laboratory workflows. Research teams should define handling, storage, chain-of-custody documentation, and any preparation requirements based on internal SOPs and the specific experimental model.
Protocol Design Considerations: NNMT-related studies can be sensitive to diet, circadian timing, baseline metabolic status, and tissue selection. Standardize confounders, pre-register endpoints where possible, and document sampling windows to strengthen reproducibility and interpretability.
Note: The information above is provided as a high-level research reference only. All experimental use must be conducted by qualified personnel in appropriately equipped facilities, following applicable regulations and institutional policies.
Each lot is supported by a Certificate of Analysis and related documentation intended to help laboratories maintain quality controls, traceability, and protocol documentation standards. COA files are typically used for internal audits, method alignment, and research recordkeeping.
Sourcing pathway-specific research compounds requires vendor transparency, lot traceability, and documentation availability. Nordsci supports research teams with clearly labeled products and COA access designed to fit into compliance-minded procurement and documentation workflows.
IMPORTANT: 5-Amino-1MQ Capsules are supplied exclusively for laboratory research use. Not intended for human consumption, clinical use, or veterinary use. Researchers are responsible for compliance with all applicable laws, regulations, and institutional policies in their jurisdiction.
