More about Kisspeptin-10 (5mg)
Kisspeptin-10 is a synthetic, C-terminally amidated decapeptide supplied exclusively for controlled laboratory research and analytical evaluation. Also identified as human metastin (45–54), the compound is commonly examined in research involving the KISS1R receptor, historically known as GPR54.
Laboratory programs may use Kisspeptin-10 to characterize receptor binding, ligand-receptor specificity, G-protein-coupled signaling, intracellular messenger activity, and related molecular pathways under controlled experimental conditions. It is not intended for human or animal consumption or use.
Kisspeptin-10 (5mg) – Research Specifications:
| Compound |
Kisspeptin-10 |
| Alternate Name |
Human metastin (45–54) |
| Quantity |
5mg per vial |
| CAS Number |
374675-21-5 |
| Molecular Formula |
C63H83N17O14 |
| Molecular Weight |
1302.4 g/mol |
| Sequence |
H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2 |
| Single-Letter Sequence |
YNWNSFGLRF-NH2 |
| Compound Type |
Synthetic amidated decapeptide |
| Primary Research Target |
KISS1R/GPR54 receptor |
| Purity / Identity |
Refer to the applicable lot-specific Certificate of Analysis |
| Appearance |
Lyophilized peptide powder |
| Storage Conditions |
Store sealed and protected from heat, light, and moisture according to the product label and COA |
| Research Use Only |
Not for human or animal consumption or use |
The listed molecular formula and molecular weight describe the parent amidated peptide. Lot-specific counterions, residual moisture, or other analytical variables may affect the reported material composition. Consult the applicable Certificate of Analysis for verified lot information.
What Is Kisspeptin-10? Research Background
Kisspeptin-10 is the amidated C-terminal decapeptide associated with the KISS1 peptide family. Its laboratory characterization commonly focuses on its interaction with KISS1R/GPR54, a G-protein-coupled receptor examined in receptor pharmacology and signal-transduction research.
Published laboratory literature describes KISS1R signaling in connection with Gq/11-mediated pathways involving phospholipase C, inositol triphosphate, diacylglycerol, intracellular calcium, and protein kinase C. These molecular relationships can be examined through receptor-binding assays, cell-based models, pathway-specific analytical methods, and other controlled experimental systems.
Experimental observations may vary according to assay design, receptor-expression system, species, cell type, material stability, analytical methodology, and environmental conditions. Findings should be interpreted within the limitations of the specific laboratory model and protocol.
Important Research Notice: NordSci makes lot-specific analytical documentation available for its research materials. Consult the applicable Certificate of Analysis for reported identity, purity, analytical methods, and test results.
THIS PRODUCT IS FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION OR USE. NOT FOR DIAGNOSTIC, THERAPEUTIC, VETERINARY, FOOD, COSMETIC, OR DIETARY-SUPPLEMENT APPLICATIONS.
Kisspeptin-10 – Key Research Applications
1. Neuroendocrine Signaling Research
Controlled laboratory models may use Kisspeptin-10 to characterize molecular signaling associated with KISS1R-expressing systems. Research variables can include receptor activation, intracellular messenger activity, calcium mobilization, and pathway-specific assay responses.
2. Hypothalamic Signaling Studies
Kisspeptin-10 may be examined in laboratory models designed to characterize signaling relationships involving KISS1R and neuroendocrine pathways. These investigations should use documented assay conditions, validated analytical methods, and appropriate experimental controls.
3. Reproductive Hormone Regulation Research
Laboratory investigations may examine the position of KISS1R signaling within broader neuroendocrine pathway models. This research context concerns molecular mechanisms and experimental signaling relationships rather than clinical, therapeutic, or consumer outcomes.
4. Endocrine Feedback Loop Investigation
Experimental models may evaluate receptor activity and downstream signaling under defined laboratory conditions. Assay variables can include receptor expression, signaling duration, concentration-dependent experimental responses, and intracellular pathway markers.
Handling and Research Use Considerations
Kisspeptin-10 (5mg) should be handled only by qualified laboratory personnel using established procedures for research peptides. Researchers should document storage conditions, sample identification, environmental exposure, analytical controls, and other variables relevant to experimental reproducibility.
Protocol Design Considerations: Results may be affected by assay format, peptide stability, receptor-expression levels, sample preparation, temperature, timing, instrumentation, and analytical methodology. Each laboratory is responsible for selecting validated procedures and maintaining appropriate records.
No dosing, administration, application, or human-use instructions are provided because this material is supplied exclusively for laboratory research.
Note: This information is provided exclusively as a laboratory research reference. All work should be conducted by qualified personnel within an appropriate laboratory environment.
Kisspeptin-10 (5mg) – Certificate of Analysis (COA)
Lot-specific Certificates of Analysis provide the applicable analytical information for Kisspeptin-10 supplied by NordSci Peptides. Depending on the testing performed, the documentation may identify reported purity, identity findings, analytical methods, and batch information.
Researchers should review the COA associated with the specific lot rather than relying on general product-page specifications for analytical verification.
Where to Buy Kisspeptin-10 for Research
NordSci Peptides supplies Kisspeptin-10 (5mg) exclusively as a laboratory research material. Laboratories evaluating peptide suppliers should review lot traceability, analytical documentation, labeled storage conditions, compound identity, and research-use restrictions before purchasing.
IMPORTANT: Kisspeptin-10 (5mg) is not for human or animal consumption or use. It is not intended for clinical, diagnostic, therapeutic, veterinary, food, cosmetic, or dietary-supplement applications. Purchasers are responsible for complying with all applicable institutional and regulatory requirements governing laboratory research materials.
Scientific References
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PubChem. Kisspeptin-10, Compound CID 25240297. Chemical identifiers, molecular formula, molecular weight, and peptide sequence.
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Oakley AE, Clifton DK, Steiner RA. Kisspeptin Signaling in the Brain. Endocrine Reviews. 2009;30(6):713–743.
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Castaño JP, et al. Intracellular Signaling Pathways Activated by Kisspeptins Through GPR54: Do Multiple Signals Underlie Function Diversity? Peptides. 2009;30(1):10–15.
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Franssen D, et al. The Kisspeptin Receptor: A Key G-Protein-Coupled Receptor in the Control of the Reproductive Axis. Best Practice & Research Clinical Endocrinology & Metabolism. 2018;32(2):107–123.