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Kisspeptin-10 (5mg)

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Product Description

Kisspeptin-10 (5mg) is a synthetic, C-terminally amidated decapeptide supplied exclusively for controlled laboratory research and analytical evaluation. This material is not for human or animal consumption or use and is not intended for diagnostic, therapeutic, veterinary, food, cosmetic, or dietary-supplement applications.

Kisspeptin-10 is also identified as human metastin (45–54). Its laboratory characterization commonly involves the KISS1R receptor, also known as GPR54, and associated G-protein-coupled receptor signaling. Experimental programs may examine receptor binding, ligand-receptor specificity, second-messenger activity, intracellular calcium responses, or related molecular pathways under controlled conditions.

Kisspeptin-10 (5mg) – Technical Specifications:

Specification Product Information
Compound Kisspeptin-10
Alternate Name Human metastin (45–54)
Quantity 5mg per vial
CAS Number 374675-21-5
Molecular Formula C63H83N17O14
Molecular Weight 1302.4 g/mol
Sequence H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Single-Letter Sequence YNWNSFGLRF-NH2
Form Lyophilized peptide powder
Purity and Identity Refer to the applicable lot-specific Certificate of Analysis
Research Classification For laboratory research use only

The listed molecular formula and molecular weight describe the parent amidated peptide. Lot-specific counterions, residual moisture, or other analytical variables may affect the reported material composition. Researchers should consult the applicable Certificate of Analysis for verified lot data.

NordSci provides lot-specific analytical documentation for research materials. Available documentation may identify analytical methods such as high-performance liquid chromatography or mass spectrometry when those methods were used for the applicable lot.

 

The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.

THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY.

Storage Guidelines

All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.

Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.

After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.

For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.

For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:

Peptide Storage and Stability: Best Practices for Every Lab

COA Lab Test

Kisspeptin-10 (5mg)

Regular Price
$65.00
Sale Price
$65.00
Regular Price
Sold Out
Unit Price
per

More about Kisspeptin-10 (5mg)

Kisspeptin-10 is a synthetic, C-terminally amidated decapeptide supplied exclusively for controlled laboratory research and analytical evaluation. Also identified as human metastin (45–54), the compound is commonly examined in research involving the KISS1R receptor, historically known as GPR54.

Laboratory programs may use Kisspeptin-10 to characterize receptor binding, ligand-receptor specificity, G-protein-coupled signaling, intracellular messenger activity, and related molecular pathways under controlled experimental conditions. It is not intended for human or animal consumption or use.

Kisspeptin-10 (5mg) – Research Specifications:

Compound Kisspeptin-10
Alternate Name Human metastin (45–54)
Quantity 5mg per vial
CAS Number 374675-21-5
Molecular Formula C63H83N17O14
Molecular Weight 1302.4 g/mol
Sequence H-Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Single-Letter Sequence YNWNSFGLRF-NH2
Compound Type Synthetic amidated decapeptide
Primary Research Target KISS1R/GPR54 receptor
Purity / Identity Refer to the applicable lot-specific Certificate of Analysis
Appearance Lyophilized peptide powder
Storage Conditions Store sealed and protected from heat, light, and moisture according to the product label and COA
Research Use Only Not for human or animal consumption or use

The listed molecular formula and molecular weight describe the parent amidated peptide. Lot-specific counterions, residual moisture, or other analytical variables may affect the reported material composition. Consult the applicable Certificate of Analysis for verified lot information.

What Is Kisspeptin-10? Research Background

Kisspeptin-10 is the amidated C-terminal decapeptide associated with the KISS1 peptide family. Its laboratory characterization commonly focuses on its interaction with KISS1R/GPR54, a G-protein-coupled receptor examined in receptor pharmacology and signal-transduction research.

Published laboratory literature describes KISS1R signaling in connection with Gq/11-mediated pathways involving phospholipase C, inositol triphosphate, diacylglycerol, intracellular calcium, and protein kinase C. These molecular relationships can be examined through receptor-binding assays, cell-based models, pathway-specific analytical methods, and other controlled experimental systems.

Experimental observations may vary according to assay design, receptor-expression system, species, cell type, material stability, analytical methodology, and environmental conditions. Findings should be interpreted within the limitations of the specific laboratory model and protocol.

Important Research Notice: NordSci makes lot-specific analytical documentation available for its research materials. Consult the applicable Certificate of Analysis for reported identity, purity, analytical methods, and test results.

THIS PRODUCT IS FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION OR USE. NOT FOR DIAGNOSTIC, THERAPEUTIC, VETERINARY, FOOD, COSMETIC, OR DIETARY-SUPPLEMENT APPLICATIONS.

Kisspeptin-10 – Key Research Applications

1. Neuroendocrine Signaling Research

Controlled laboratory models may use Kisspeptin-10 to characterize molecular signaling associated with KISS1R-expressing systems. Research variables can include receptor activation, intracellular messenger activity, calcium mobilization, and pathway-specific assay responses.

2. Hypothalamic Signaling Studies

Kisspeptin-10 may be examined in laboratory models designed to characterize signaling relationships involving KISS1R and neuroendocrine pathways. These investigations should use documented assay conditions, validated analytical methods, and appropriate experimental controls.

3. Reproductive Hormone Regulation Research

Laboratory investigations may examine the position of KISS1R signaling within broader neuroendocrine pathway models. This research context concerns molecular mechanisms and experimental signaling relationships rather than clinical, therapeutic, or consumer outcomes.

4. Endocrine Feedback Loop Investigation

Experimental models may evaluate receptor activity and downstream signaling under defined laboratory conditions. Assay variables can include receptor expression, signaling duration, concentration-dependent experimental responses, and intracellular pathway markers.

Handling and Research Use Considerations

Kisspeptin-10 (5mg) should be handled only by qualified laboratory personnel using established procedures for research peptides. Researchers should document storage conditions, sample identification, environmental exposure, analytical controls, and other variables relevant to experimental reproducibility.

Protocol Design Considerations: Results may be affected by assay format, peptide stability, receptor-expression levels, sample preparation, temperature, timing, instrumentation, and analytical methodology. Each laboratory is responsible for selecting validated procedures and maintaining appropriate records.

No dosing, administration, application, or human-use instructions are provided because this material is supplied exclusively for laboratory research.

Note: This information is provided exclusively as a laboratory research reference. All work should be conducted by qualified personnel within an appropriate laboratory environment.

Kisspeptin-10 (5mg) – Certificate of Analysis (COA)

Lot-specific Certificates of Analysis provide the applicable analytical information for Kisspeptin-10 supplied by NordSci Peptides. Depending on the testing performed, the documentation may identify reported purity, identity findings, analytical methods, and batch information.

Researchers should review the COA associated with the specific lot rather than relying on general product-page specifications for analytical verification.

Where to Buy Kisspeptin-10 for Research

NordSci Peptides supplies Kisspeptin-10 (5mg) exclusively as a laboratory research material. Laboratories evaluating peptide suppliers should review lot traceability, analytical documentation, labeled storage conditions, compound identity, and research-use restrictions before purchasing.

IMPORTANT: Kisspeptin-10 (5mg) is not for human or animal consumption or use. It is not intended for clinical, diagnostic, therapeutic, veterinary, food, cosmetic, or dietary-supplement applications. Purchasers are responsible for complying with all applicable institutional and regulatory requirements governing laboratory research materials.

Scientific References

  1. PubChem. Kisspeptin-10, Compound CID 25240297. Chemical identifiers, molecular formula, molecular weight, and peptide sequence.
  2. Oakley AE, Clifton DK, Steiner RA. Kisspeptin Signaling in the Brain. Endocrine Reviews. 2009;30(6):713–743.
  3. Castaño JP, et al. Intracellular Signaling Pathways Activated by Kisspeptins Through GPR54: Do Multiple Signals Underlie Function Diversity? Peptides. 2009;30(1):10–15.
  4. Franssen D, et al. The Kisspeptin Receptor: A Key G-Protein-Coupled Receptor in the Control of the Reproductive Axis. Best Practice & Research Clinical Endocrinology & Metabolism. 2018;32(2):107–123.