NAD+ (1000 mg)

NAD – Product Description

NAD (nicotinamide adenine dinucleotide) is a high-purity research compound used to investigate cellular energy transfer, redox balance, and metabolic signaling pathways in preclinical models. As a central cofactor in oxidative metabolism and mitochondrial function, NAD is a core focus in laboratory research programs exploring bioenergetics, stress responses, and healthy aging biology.

This NAD research product is manufactured under stringent quality controls and supported by third-party analytical testing, providing investigators with a consistent, research-grade material for in vitro and in vivo experimental designs.

NAD Research Product Specifications:

What Is NAD? Research Background and Mechanistic Focus

NAD is a ubiquitous redox cofactor that participates in thousands of metabolic reactions, including glycolysis, the tricarboxylic acid (TCA) cycle, and oxidative phosphorylation. In preclinical research, NAD is central to investigations of mitochondrial function, cellular energy status, and the balance between oxidized (NAD⁺) and reduced (NADH) forms under different physiological and stress conditions.

Beyond its classical role in electron transfer, NAD also serves as a substrate for several key enzyme families, including sirtuins and PARPs, which are actively studied in the context of DNA repair, chromatin remodeling, metabolic adaptation, and cellular stress responses. These diverse functions make NAD a critical lever in experimental systems focused on metabolism, resilience, and aging.

Key NAD Research Areas

Metabolic and Mitochondrial Function

In metabolic research frameworks, NAD is utilized to probe mitochondrial respiration, ATP production, and the impact of nutrient availability or energetic stress on cellular redox balance. Investigators frequently monitor NAD/NADH ratios as readouts of metabolic state in cell culture and animal models.

Cellular Stress, DNA Repair, and Signaling

NAD-dependent enzymes such as PARPs and sirtuins are commonly investigated for their roles in DNA damage responses, chromatin structure, and transcriptional regulation under oxidative or genotoxic stress. NAD manipulation in research settings enables teams to evaluate how changes in NAD pools influence downstream repair pathways and stress-adaptation programs.

Aging, Longevity, and Systemic Resilience

Because NAD availability is closely linked to mitochondrial function and metabolic flexibility, it is frequently integrated into preclinical studies of healthy aging and resilience. These models focus on mechanistic endpoints such as mitochondrial health markers, stress tolerance, and inflammatory signaling, not on clinical outcomes or human treatment recommendations.

NAD Reconstitution and Laboratory Handling

General Reconstitution Framework for Research Use:

In research laboratories, lyophilized NAD is typically reconstituted with sterile water for injection, buffered saline, or another institution-approved vehicle. Final concentrations are defined by the experimental model, assay format, and targeted readouts.

Standard good-laboratory practices often include:

• Allowing the vial to equilibrate to room temperature before opening to minimize condensation
• Adding the selected sterile diluent slowly along the inner vial wall to promote even dissolution
• Gently swirling until fully dissolved rather than vigorous shaking
• Aliquoting reconstituted NAD to reduce repeated freeze–thaw cycles
• Documenting concentration, diluent, lot number, and reconstitution date in laboratory records

All specific concentration ranges, schedules, and time courses must be determined by the research institution. This information is provided solely as a general laboratory reference framework, not as guidance for clinical or human use.

Quality Control, COA, and Research Compliance

Each NAD lot is supported by independent third-party analytical testing to verify identity and purity. Certificate of Analysis (COA) documentation is available for research groups that require detailed characterization, including HPLC chromatograms and mass spectrometry profiles, to support internal QA, regulatory, and audit processes.

Typical NAD-focused research workflows include:

• Confirming that institutional IACUC, biosafety, or in vitro review protocols support the planned use of NAD
• Maintaining full traceability of lot numbers, storage conditions, and in-use durations
• Including vehicle-only controls for clear interpretation of NAD-specific effects
• Capturing NAD-related methods transparently in reports, SOPs, and manuscripts

Where to Source NAD for Research

Research groups typically prioritize suppliers that specialize in research-only biochemicals and provide comprehensive analytical documentation. Nordsci Peptides focuses on research-grade compounds with clear positioning for laboratory use, supported by COA documentation and batch-level traceability for institutional compliance.

Centralizing NAD sourcing and documentation under consistent internal SOPs enables laboratories to integrate NAD into broader metabolic, mitochondrial, and aging research programs while preserving reproducibility and data integrity across studies.

THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE OR CONDITION.

ALL ARTICLES AND PRODUCT INFORMATION PROVIDED ON THIS WEBSITE ARE FOR INFORMATONAL AND EDUCATIONAL PURPOSES ONLY.

The products offered on this website are furnished for in-vitro studies only. In-vitro studies (Latin: in glass) are performed outside of the body.  These products are not medicines or drugs and have not been approved by the FDA to prevent, treat or cure any medical condition, ailment or disease.  Bodily introduction of any kind into humans or animals is strictly forbidden by law.