GHRP-6 is a potent stimulator of natural growth hormone release from the anterior pituitary gland, and it also functions as a ghrelin/growth hormone receptor agonist. GHRP-6 is orally and sublingually active and exhibits moderate to high selectivity.
It is one of several ghrelin analogs developed in recent decades, and research has shown that it has positive effects on various bodily functions, including heart muscle cells, memory formation, scar formation, sex motivation, and neurons involved in Parkinson’s disease.
Studies have found that GHRP-6 can improve memory formation by helping to solidify newly formed memories and convert short-term memories into long-term storage. It has also been shown to protect brain tissue during acute stroke and rescue memory deficits following a stroke.
GHRP-6 may be useful in protecting neurons in the substantia nigra and slowing or preventing the onset of Parkinson’s disease. In addition, the peptide is highly effective in wound healing, reducing the appearance of scar tissue and preventing the development of hypertrophic scars.
Furthermore, GHRP-6 has been found to reduce heart problems by protecting heart cells from damage by free radicals, and it can also alter sex motivation and mood by modulating sex behavior and reward-seeking behavior.
Studies have also shown that it can decrease depression and improve function in parts of the brain associated with mood, particularly in the setting of stress. GHRP-6 exhibits minimal to moderate side effects, and in mice, it has low oral and excellent subcutaneous bioavailability.
The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.
THIS PRODUCT IS NOT INTENDED TO TREAT, CURE, OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY.
All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.
Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.
After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.
For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.
For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:
GHRP-6 (Growth Hormone Releasing Peptide-6) is a synthetic hexapeptide engineered for advanced research into growth hormone secretagogue receptor (GHS-R1a) signaling, ghrelin-mimetic pathways, and endocrine–metabolic interactions in preclinical models. This research-only peptide is produced via chemical synthesis and supplied as a lyophilized powder to support controlled protocol design and reproducible data collection.
As a classic growth hormone secretagogue, GHRP-6 has been widely utilized in animal and in vitro systems to interrogate GH pulse dynamics, appetite regulation mechanisms, and downstream IGF-1–linked signaling cascades. Nordsci GHRP-6 is manufactured to research-grade specifications with rigorous analytical verification, making it a fit-for-purpose tool compound for laboratories studying the GH/ghrelin axis.
GHRP-6 Research Peptide Specifications:
| Unit Size | 5 or 10mg/vial |
| Unit Quantity | 1 vial |
| Purity (HPLC) | ≥ 99% |
| Peptide Type | Growth Hormone Releasing Peptide-6 (GHRP-6) |
| Sequence | His–D-Trp–Ala–Trp–D-Phe–Lys–NH2 |
| Molecular Formula | C46H56N12O6 |
| Molecular Weight | ~873.0 g/mol |
| Appearance | Lyophilized white to off-white powder |
| Source | Chemical synthesis |
| Storage Conditions | Store lyophilized GHRP-6 at -20 °C in a dry, dark environment. After reconstitution, maintain aliquots refrigerated and use within protocol-defined stability windows. |
| Research Use Only | For laboratory research use only. Not for human consumption, clinical treatment, diagnostic use, or veterinary applications. |
GHRP-6 is one of the earliest and most extensively characterized synthetic growth hormone secretagogues. It exerts its effects primarily through agonism of the GHS-R1a (ghrelin) receptor in the pituitary and hypothalamus. In preclinical systems, this receptor engagement drives pulsatile GH release, alters appetite-related pathways, and modulates downstream anabolic and metabolic signaling cascades.
Key research domains where GHRP-6 is frequently utilized include:
Because GHRP-6 is a prototypical GHS, it is frequently deployed as a reference compound in experimental designs evaluating newer secretagogues, multi-peptide stacks, and GH-axis intervention strategies under controlled conditions.
In preclinical models, GHRP-6 has been shown to reliably stimulate GH release in a pulsatile fashion. Research teams often use GHRP-6 to:
GHRP-6’s ghrelin-mimetic activity extends beyond GH release. Animal studies have leveraged GHRP-6 to explore:
Because growth hormone can influence lean mass, lipolysis, and tissue turnover in preclinical systems, GHRP-6 is frequently incorporated into broader research frameworks where investigators track:
Important Research Notice: All findings referenced in the GHRP-6 literature arise from animal and in vitro models. GHRP-6 from Nordsci is not a drug, has not been evaluated for safety or efficacy in humans, and must not be used in any clinical, self-experimentation, or non-research context.
Reconstitution Guidelines (Research Use Only):
Reconstitute each vial of GHRP-6 with an appropriate sterile laboratory diluent (for example, bacteriostatic water or another protocol-approved vehicle) to reach the desired working concentration. Specific concentrations, exposure durations, and scheduling should be defined by your institutional protocols, existing ghrelin/secretagogue literature, and study objectives.
Note: All experimental designs involving GHRP-6 must be reviewed and approved by the relevant institutional animal care and ethics bodies. Handling, storage, and disposal should follow local laboratory safety guidelines for research-only peptides.
Each lot of Nordsci GHRP-6 is subjected to independent third-party analytical testing to confirm identity and purity. Typical COA documentation includes:
COAs are available for qualified research organizations to support internal quality systems, protocol design, and audit requirements.
GHRP-6 should be procured exclusively from specialized peptide suppliers that clearly label products for research use, maintain documented analytical testing, and operate under robust quality frameworks. Nordsci Peptides focuses on providing GHRP-6 and complementary GH-axis research compounds to professional investigators and laboratories.
Before incorporating GHRP-6 into any in vitro or in vivo protocol, research teams should ensure that:
THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE OR CONDITION.
