More about FOXO4-DRI (10mg)
FOXO4-DRI (10mg) is a synthetic research peptide intended for controlled in vitro experimentation and analytical evaluation. The material is studied in laboratory systems involving the FOXO4-p53 interaction, transcription-factor activity, cellular stress signaling, cell-cycle regulation, and senescence-associated molecular pathways.
Cellular senescence is an experimentally defined state in which a cell undergoes persistent cell-cycle arrest while retaining measurable metabolic and signaling activity. Laboratory investigations use cellular, biochemical, and molecular assays to characterize the regulatory networks associated with this state.
FOXO4-DRI is not a pharmaceutical product, dietary supplement, food, cosmetic, or clinical material. No dosing, administration, or application guidance is provided.
FOXO4-DRI (10mg) – Research Specifications:
| Compound |
FOXO4-DRI |
| Quantity |
10mg per vial |
| Compound Type |
Synthetic D-retro-inverso research peptide |
| Research Classification |
Laboratory research material |
| Form |
Lyophilized peptide powder |
| Molecular Formula |
Refer to the applicable product documentation or lot-specific Certificate of Analysis |
| Molecular Weight |
Refer to the applicable product documentation or lot-specific Certificate of Analysis |
| CAS Number |
Refer to the applicable product documentation or lot-specific Certificate of Analysis |
| Sequence |
Refer to the applicable product documentation or lot-specific Certificate of Analysis |
| Purity and Identity |
Reported in the lot-specific Certificate of Analysis |
| Storage Conditions |
Store sealed under the conditions stated on the product label and applicable Certificate of Analysis |
| Testing Documentation |
Lot-specific analytical documentation is available through the COA Library |
| Research Use Only |
Not for human or animal consumption or in vivo procedures |
What Is FOXO4-DRI? Research Background
FOXO4-DRI is a synthetic peptide developed for laboratory investigation of molecular interactions involving FOXO4 and p53. FOXO4 belongs to the forkhead box O family of transcription factors, while p53 is a regulatory protein examined in cell-cycle, genomic-stability, and stress-response research.
Experimental programs involving this peptide may use binding assays, cultured-cell systems, protein-interaction studies, or other controlled analytical methods to examine FOXO4-p53 pathway activity. Results can vary according to the selected model, assay conditions, material concentration, exposure period, detection method, and laboratory controls.
Research involving FOXO4-DRI should remain limited to properly equipped laboratory environments and appropriately qualified personnel. References to molecular pathways describe areas of scientific investigation and do not indicate a clinical or consumer application.
Important Research Notice: Nordsci research materials are accompanied by lot-specific analytical documentation. Consult the applicable Certificate of Analysis for reported identity, purity, testing methods, and other analytical findings.
THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR IN VIVO, VETERINARY, DIAGNOSTIC, THERAPEUTIC, FOOD, COSMETIC, OR DIETARY SUPPLEMENT USE.
FOXO4-DRI – Key Research Applications
1. Cellular Senescence Research
FOXO4-DRI may be incorporated into controlled in vitro experiments examining molecular markers, protein interactions, and signaling events associated with cellular senescence. Appropriate positive, negative, and vehicle controls should be established according to the selected research model.
2. Transcription Factor Signaling Studies
Researchers may use FOXO4-DRI in biochemical or cellular assays designed to characterize interactions involving FOXO4, p53, and related transcriptional signaling components. These experiments can examine binding behavior, pathway activity, or changes in defined molecular markers.
3. Oxidative Stress Response Research
Controlled laboratory models may examine FOXO-associated signaling under experimentally induced cellular stress conditions. Study design should account for variables such as cell type, assay platform, exposure conditions, detection method, and experimental duration.
4. Longevity Pathway Investigation
FOXO4-DRI may be used in basic research examining molecular pathways associated with senescence and cellular lifespan regulation. This research classification does not indicate a consumer longevity application, clinical effect, or therapeutic use.
Handling and Research Use Considerations
FOXO4-DRI (10mg) should be handled by qualified laboratory personnel using established procedures for synthetic peptide research materials. Laboratories should review the product label, Certificate of Analysis, and applicable safety documentation before handling the material.
Maintain complete records for lot number, receipt date, storage conditions, material transfers, experimental conditions, and analytical results. Use appropriate personal protective equipment and containment procedures based on the laboratory’s institutional requirements and risk assessment.
Protocol Design Considerations: Experimental results may be affected by material concentration, assay type, cell model, incubation conditions, detection methodology, environmental conditions, and control selection. These variables should be defined and documented before research begins.
Note: This information is provided solely for laboratory identification, storage, handling, and research-planning purposes. It does not provide dosing, administration, clinical, veterinary, or consumer-use instructions.
FOXO4-DRI (10mg) – Certificate of Analysis (COA)
Lot-specific analytical documentation is available for FOXO4-DRI supplied by Nordsci Peptides. The applicable Certificate of Analysis identifies the tested lot and reports the analytical findings generated for that material.
Researchers should review the Certificate of Analysis before use and retain the document with the laboratory’s inventory, experimental, and traceability records. Testing methods and reported specifications should be verified directly from the certificate assigned to the purchased lot.
Where to Buy FOXO4-DRI for Research
Nordsci Peptides supplies FOXO4-DRI (10mg) exclusively as a laboratory research material. Each vial is intended for qualified researchers and organizations conducting controlled in vitro experimentation or analytical evaluation.
Lot-specific documentation is available through the Nordsci COA Library for laboratories evaluating product identity, analytical findings, and material traceability.
IMPORTANT: FOXO4-DRI (10mg) is not for human or animal consumption. It is not a drug, food, cosmetic, dietary supplement, or veterinary product and is not intended for diagnostic or therapeutic use. The purchaser is responsible for complying with applicable institutional, local, state, federal, and international requirements governing laboratory research materials.
Scientific References
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Baar, M.P., et al. “Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.” Cell. 2017;169(1):132–147.e16.
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Bourgeois, B., and Madl, T. “Regulation of Cellular Senescence via the FOXO4-p53 Axis.” FEBS Letters. 2018;592(12):2083–2097.