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FOX04-DRI (10mg)

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Product Description

FOXO4-DRI is a synthetic D-retro-inverso peptide supplied exclusively for controlled laboratory research. It is used in experimental systems examining molecular interactions involving the FOXO4 transcription factor and the p53 signaling protein.

FOXO4 and p53 are studied in connection with transcriptional regulation, cellular stress signaling, cell-cycle control, genomic stability, and senescence-associated molecular pathways. FOXO4-DRI provides researchers with a defined peptide material for conducting in vitro assays, analytical evaluations, and controlled biochemical experiments involving these signaling systems.

Every lot is accompanied by analytical documentation identifying the tested material and reporting lot-specific quality data. Researchers should consult the applicable Certificate of Analysis before beginning an experiment.

 

The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.

THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY."

Storage Guidelines

All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.

Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.

After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.

For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.

For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:

Peptide Storage and Stability: Best Practices for Every Lab

COA Lab Test

FOX04-DRI (10mg)

Regular Price
$300.00
Sale Price
$300.00
Regular Price
Sold Out
Unit Price
per

More about FOXO4-DRI (10mg)

FOXO4-DRI (10mg) is a synthetic research peptide intended for controlled in vitro experimentation and analytical evaluation. The material is studied in laboratory systems involving the FOXO4-p53 interaction, transcription-factor activity, cellular stress signaling, cell-cycle regulation, and senescence-associated molecular pathways.

Cellular senescence is an experimentally defined state in which a cell undergoes persistent cell-cycle arrest while retaining measurable metabolic and signaling activity. Laboratory investigations use cellular, biochemical, and molecular assays to characterize the regulatory networks associated with this state.

FOXO4-DRI is not a pharmaceutical product, dietary supplement, food, cosmetic, or clinical material. No dosing, administration, or application guidance is provided.

FOXO4-DRI (10mg) – Research Specifications:

Compound FOXO4-DRI
Quantity 10mg per vial
Compound Type Synthetic D-retro-inverso research peptide
Research Classification Laboratory research material
Form Lyophilized peptide powder
Molecular Formula Refer to the applicable product documentation or lot-specific Certificate of Analysis
Molecular Weight Refer to the applicable product documentation or lot-specific Certificate of Analysis
CAS Number Refer to the applicable product documentation or lot-specific Certificate of Analysis
Sequence Refer to the applicable product documentation or lot-specific Certificate of Analysis
Purity and Identity Reported in the lot-specific Certificate of Analysis
Storage Conditions Store sealed under the conditions stated on the product label and applicable Certificate of Analysis
Testing Documentation Lot-specific analytical documentation is available through the COA Library
Research Use Only Not for human or animal consumption or in vivo procedures

What Is FOXO4-DRI? Research Background

FOXO4-DRI is a synthetic peptide developed for laboratory investigation of molecular interactions involving FOXO4 and p53. FOXO4 belongs to the forkhead box O family of transcription factors, while p53 is a regulatory protein examined in cell-cycle, genomic-stability, and stress-response research.

Experimental programs involving this peptide may use binding assays, cultured-cell systems, protein-interaction studies, or other controlled analytical methods to examine FOXO4-p53 pathway activity. Results can vary according to the selected model, assay conditions, material concentration, exposure period, detection method, and laboratory controls.

Research involving FOXO4-DRI should remain limited to properly equipped laboratory environments and appropriately qualified personnel. References to molecular pathways describe areas of scientific investigation and do not indicate a clinical or consumer application.

Important Research Notice: Nordsci research materials are accompanied by lot-specific analytical documentation. Consult the applicable Certificate of Analysis for reported identity, purity, testing methods, and other analytical findings.

THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR IN VIVO, VETERINARY, DIAGNOSTIC, THERAPEUTIC, FOOD, COSMETIC, OR DIETARY SUPPLEMENT USE.

FOXO4-DRI – Key Research Applications

1. Cellular Senescence Research

FOXO4-DRI may be incorporated into controlled in vitro experiments examining molecular markers, protein interactions, and signaling events associated with cellular senescence. Appropriate positive, negative, and vehicle controls should be established according to the selected research model.

2. Transcription Factor Signaling Studies

Researchers may use FOXO4-DRI in biochemical or cellular assays designed to characterize interactions involving FOXO4, p53, and related transcriptional signaling components. These experiments can examine binding behavior, pathway activity, or changes in defined molecular markers.

3. Oxidative Stress Response Research

Controlled laboratory models may examine FOXO-associated signaling under experimentally induced cellular stress conditions. Study design should account for variables such as cell type, assay platform, exposure conditions, detection method, and experimental duration.

4. Longevity Pathway Investigation

FOXO4-DRI may be used in basic research examining molecular pathways associated with senescence and cellular lifespan regulation. This research classification does not indicate a consumer longevity application, clinical effect, or therapeutic use.

Handling and Research Use Considerations

FOXO4-DRI (10mg) should be handled by qualified laboratory personnel using established procedures for synthetic peptide research materials. Laboratories should review the product label, Certificate of Analysis, and applicable safety documentation before handling the material.

Maintain complete records for lot number, receipt date, storage conditions, material transfers, experimental conditions, and analytical results. Use appropriate personal protective equipment and containment procedures based on the laboratory’s institutional requirements and risk assessment.

Protocol Design Considerations: Experimental results may be affected by material concentration, assay type, cell model, incubation conditions, detection methodology, environmental conditions, and control selection. These variables should be defined and documented before research begins.

Note: This information is provided solely for laboratory identification, storage, handling, and research-planning purposes. It does not provide dosing, administration, clinical, veterinary, or consumer-use instructions.

FOXO4-DRI (10mg) – Certificate of Analysis (COA)

Lot-specific analytical documentation is available for FOXO4-DRI supplied by Nordsci Peptides. The applicable Certificate of Analysis identifies the tested lot and reports the analytical findings generated for that material.

Researchers should review the Certificate of Analysis before use and retain the document with the laboratory’s inventory, experimental, and traceability records. Testing methods and reported specifications should be verified directly from the certificate assigned to the purchased lot.

Where to Buy FOXO4-DRI for Research

Nordsci Peptides supplies FOXO4-DRI (10mg) exclusively as a laboratory research material. Each vial is intended for qualified researchers and organizations conducting controlled in vitro experimentation or analytical evaluation.

Lot-specific documentation is available through the Nordsci COA Library for laboratories evaluating product identity, analytical findings, and material traceability.

IMPORTANT: FOXO4-DRI (10mg) is not for human or animal consumption. It is not a drug, food, cosmetic, dietary supplement, or veterinary product and is not intended for diagnostic or therapeutic use. The purchaser is responsible for complying with applicable institutional, local, state, federal, and international requirements governing laboratory research materials.

Scientific References

  1. Baar, M.P., et al. “Targeted Apoptosis of Senescent Cells Restores Tissue Homeostasis in Response to Chemotoxicity and Aging.” Cell. 2017;169(1):132–147.e16.
  2. Bourgeois, B., and Madl, T. “Regulation of Cellular Senescence via the FOXO4-p53 Axis.” FEBS Letters. 2018;592(12):2083–2097.