Melanotan 2 (MT-2) is a synthetic cyclic peptide supplied as a lyophilized material for controlled laboratory research and analytical evaluation. It is commonly studied in vitro in connection with melanocortin receptor binding, receptor-mediated signaling, and melanocyte-derived cellular models.
MT-2 is an analog associated with the alpha-melanocyte-stimulating hormone research lineage. Laboratory studies may use the compound to characterize interactions with melanocortin receptor subtypes and document downstream molecular activity under defined assay conditions. These research contexts do not establish clinical safety, effectiveness, or suitability for human or veterinary applications.
Lot-specific analytical documentation is available through the Nordsci Certificate of Analysis Library. Researchers should review the COA associated with the applicable product lot before beginning an experiment.
The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.
THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY.
All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.
Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.
After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.
For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.
For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:
Melanotan II, commonly abbreviated MT-2, is a synthetic cyclic peptide supplied for controlled laboratory research and analytical evaluation. It is commonly examined in vitro in studies involving melanocortin receptor binding, receptor-mediated signaling, melanocyte-derived cellular models, and associated molecular-response assays.
MT-2 is connected to the alpha-melanocyte-stimulating hormone research lineage and provides laboratories with a defined compound for receptor characterization and comparative assay development. References to pigmentation or melanocyte activity identify experimental research categories only and do not represent cosmetic, therapeutic, or human-use claims.
Melanotan II Research Peptide Specifications:
| Unit Size | 10mg per vial |
| Unit Quantity | 1 vial |
| Sequence | Ac-Nle-cyclo(-β-Asp-His-D-Phe-Arg-Trp-ε-Lys-NH2) |
| Molecular Formula | C50H69N15O9 |
| Molecular Weight | Approximately 1024.2 g/mol |
| CAS Number | 121062-08-6 |
| Form | Lyophilized powder |
| Source | Chemical synthesis |
| Purity / Identity | Refer to the lot-specific Certificate of Analysis |
| Analytical Documentation | Lot-specific documentation may report HPLC, mass spectrometry, or other applicable analytical results |
| Storage Conditions | Store sealed at −20°C or below and protect from light, heat, and moisture unless otherwise stated in the applicable documentation |
| Research Classification | Laboratory research and analytical use only |
| Restrictions | Not for human or animal consumption or in vivo, diagnostic, therapeutic, food, drug, cosmetic, or dietary-supplement use |
Melanotan II is a synthetic peptide used in controlled laboratory studies examining the melanocortin receptor system. Melanocortin receptors are G protein-coupled receptors that can be evaluated through receptor-binding assays, second-messenger measurements, and other defined analytical methods.
Laboratory research may examine MT-2 in connection with MC1R and other melanocortin receptor subtypes. Experimental endpoints can include receptor affinity, selectivity, concentration-dependent activity, intracellular signaling markers, and assay-specific cellular responses.
References to melanogenesis, pigmentation signaling, or melanocyte activity describe laboratory models and measurable experimental endpoints. They do not indicate that Melanotan II is intended to alter human or animal appearance, physiology, behavior, appetite, or any other outcome.
Experimental findings must be interpreted within the limitations of the selected model, controls, exposure conditions, analytical instrumentation, and acceptance criteria.
Important Research Notice: Nordsci research materials are supplied with access to lot-specific analytical documentation. Researchers should consult the applicable Certificate of Analysis for reported identity and purity information.
THIS PRODUCT IS INTENDED EXCLUSIVELY FOR LABORATORY RESEARCH. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR IN VIVO, DIAGNOSTIC, THERAPEUTIC, FOOD, DRUG, COSMETIC, OR DIETARY-SUPPLEMENT USE.
Controlled in vitro studies may use MT-2 in melanocyte-derived experimental systems to observe predefined markers associated with melanocortin receptor activity and melanogenesis-related signaling.
Endpoints may include receptor engagement, intracellular messenger activity, enzyme-associated markers, or other measurements selected through validated laboratory procedures. Findings remain specific to the model and conditions used.
MT-2 may be incorporated into laboratory models containing melanocyte-derived or other skin-associated cell types. These studies can help researchers distinguish melanocortin receptor activity from unrelated molecular pathways within a controlled experimental system.
References to skin or dermal models describe the source or classification of the experimental material. They do not indicate cosmetic use, tanning use, dermatological application, or an effect on human or animal tissue.
Receptor-focused laboratories may use MT-2 to examine binding affinity, receptor selectivity, second-messenger activity, and concentration-dependent responses under standardized in vitro conditions.
Reliable interpretation requires appropriate controls, validated analytical methods, documented material identity, and consistent assay conditions. Researchers should avoid extending in vitro findings beyond the limitations of the experimental model.
MT-2 may be included in comparative studies designed to distinguish the behavior of different melanocortin-related research compounds. Laboratories can evaluate compounds across consistent receptor panels, cell models, exposure periods, and analytical endpoints.
Comparative findings describe relative activity under the specified laboratory conditions. They do not establish clinical equivalence, therapeutic value, safety, or suitability for human or veterinary use.
Melanotan II should be handled only by qualified laboratory personnel using established procedures for synthetic peptide research materials. Laboratories should document product receipt, lot identification, storage conditions, sample allocation, analytical methods, and disposal.
No reconstitution volume, diluent selection, concentration, dosing, injection, administration, or in vivo application guidance is provided. Those subjects fall outside the intended scope of this research-material description.
Protocol design considerations include:
Note: This information is provided exclusively as a laboratory research reference. All work should be conducted by qualified personnel in appropriately equipped facilities and in accordance with applicable institutional requirements.
Lot-specific Certificates of Analysis provide analytical information associated with the applicable Melanotan II product lot. Documentation may include identity, purity, testing methodology, and other reported analytical results.
Researchers should confirm that the lot number on the vial corresponds with the lot number shown on the applicable COA. Analytical findings apply only to the tested lot and should not be interpreted as evidence of clinical safety, effectiveness, or approval for human or veterinary use.
Nordsci Peptides supplies Melanotan II (10mg) as a laboratory research material with access to lot-specific analytical documentation. Laboratories should evaluate compound identity, reported analytical results, storage requirements, batch traceability, and institutional procurement standards before use.
IMPORTANT: Melanotan II is sold exclusively for laboratory research and analytical use. It is not a drug, food, dietary supplement, cosmetic, or therapeutic product. It is not approved for human or veterinary use and must not be used for consumption, diagnosis, treatment, prevention, cosmetic application, or any in vivo procedure.
