AICAR (5-Aminoimidazole-4-carboxamide ribonucleoside), also known as acadesine or AICA riboside, is a synthetic nucleoside analog supplied for controlled laboratory and analytical research.
For laboratory research use only. Not for human or animal consumption.
AICAR is commonly used as an in-vitro research tool in experiments involving AMP-activated protein kinase (AMPK)-related signaling, purine nucleotide pathways, and biochemical assay development. References to these pathways describe areas of laboratory investigation only and do not imply a diagnostic, therapeutic, or consumer application.
AICAR (50mg) – Research Specifications:
| Specification | Details |
|---|---|
| Compound | AICAR |
| Chemical Name | 5-Aminoimidazole-4-carboxamide ribonucleoside |
| Alternate Names | Acadesine; AICA riboside |
| Quantity | 50mg per vial |
| Molecular Formula | C₉H₁₄N₄O₅ |
| Molecular Weight | 258.23 g/mol |
| CAS Number | 2627-69-2 |
| Sequence | Not applicable; AICAR is not a peptide |
| Form | Research material; consult the vial label and batch-specific COA |
| Purity / Identity | Refer to the batch-specific Certificate of Analysis |
| Analytical Documentation | HPLC and/or mass-spectrometry documentation, as applicable to the lot |
| Research Classification | Laboratory research use only |
NordSci provides batch-specific analytical documentation for its research materials. Consult the applicable Certificate of Analysis for verified identity, purity, test methods, and lot information.
The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.
THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY.
All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.
Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.
After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.
For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.
For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:
AICAR is a synthetic nucleoside analog used in controlled laboratory research involving AMP-activated protein kinase (AMPK)-related biochemical pathways and purine nucleotide metabolism. Within experimental systems, AICAR may be converted intracellularly to an AMP analog commonly identified as ZMP. Researchers use this relationship to examine defined molecular interactions, pathway responses, and assay conditions.
This information describes AICAR's identity and established role as a laboratory research tool. It does not represent evidence of safety, effectiveness, or suitability for any human, veterinary, diagnostic, or therapeutic application.
AICAR (50mg) – Research Specifications:
| Compound | AICAR |
| Chemical Name | 5-Aminoimidazole-4-carboxamide ribonucleoside |
| Alternate Names | Acadesine; AICA riboside |
| Quantity | 50mg per vial |
| Molecular Formula | C₉H₁₄N₄O₅ |
| Molecular Weight | 258.23 g/mol |
| CAS Number | 2627-69-2 |
| Sequence | Not applicable; AICAR is not a peptide |
| Form | Research material; consult the vial label and batch-specific Certificate of Analysis |
| Purity / Identity | Refer to the batch-specific Certificate of Analysis for analytical verification |
| Analytical Documentation | HPLC and/or mass-spectrometry documentation, as applicable to the lot |
| Storage Conditions | Follow the product label and batch-specific documentation. Keep sealed and protected from heat, direct light, moisture, contamination, and repeated temperature changes. |
| Research Classification | Supplied exclusively for controlled laboratory research. Not for human or animal consumption. |
AICAR, also known as acadesine or AICA riboside, is a small-molecule research compound rather than a peptide. Its chemical structure and relationship with nucleotide-associated biochemical pathways make it suitable for carefully controlled in-vitro experiments.
Laboratory studies involving AICAR may evaluate AMPK-associated signaling, nucleotide metabolism, enzyme activity, or analytical assay performance. Experimental observations depend on the selected model, controls, material specifications, and protocol conditions established by the investigating laboratory.
References to these pathways describe areas of laboratory investigation only. They do not imply that AICAR is suitable for human use, animal use, diagnosis, treatment, prevention, or any other clinical application.
Important Research Notice: NordSci research materials are supported by batch-specific analytical documentation. Laboratories should consult the applicable Certificate of Analysis for compound identity, analytical purity, test methods, and traceability information.
THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR HUMAN OR VETERINARY IN-VIVO USE. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE OR CONDITION.
AICAR may be used in controlled in-vitro experiments examining AMPK-associated biochemical signaling and defined pathway responses.
Researchers may include AICAR in laboratory models involving purine biosynthesis, nucleotide intermediates, and related enzyme systems.
AICAR may be incorporated into validated laboratory assays designed to examine specific molecular interactions under controlled experimental conditions.
Laboratories may use AICAR in analytical-method development, reference comparisons, or other experiments requiring documented compound identity and lot traceability.
AICAR (50mg) should be handled by qualified laboratory personnel using established procedures for research chemicals. Personnel should review the vial label, safety documentation, and batch-specific Certificate of Analysis before beginning any experiment.
Environmental conditions, assay design, material handling, controls, and documentation should remain consistent throughout a research program. Each laboratory is responsible for determining whether the material and proposed experiment comply with applicable institutional, local, state, and federal requirements.
No dosing, reconstitution, administration, or human or animal application instructions are provided or implied.
This information is provided strictly for laboratory research reference purposes. All experiments should be conducted by qualified personnel within appropriately controlled laboratory environments.
Batch-specific Certificates of Analysis provide available analytical information for AICAR (50mg), including compound identity, reported purity, applicable test methods, and lot documentation.
Researchers should review the Certificate of Analysis associated with the purchased lot rather than relying on generalized product information.
Laboratories sourcing AICAR should evaluate compound identity, batch traceability, storage requirements, and available analytical documentation. NordSci supplies AICAR (50mg) as a research material with lot-specific documentation available through its COA Library.
IMPORTANT: AICAR (50mg) is supplied exclusively for controlled laboratory research. It is not a drug, dietary supplement, food, cosmetic, or medical product. It is not approved for human consumption, veterinary use, diagnostic procedures, therapeutic applications, or human or animal in-vivo research.
