VIP (6mg) – Product Description
VIP (Vasoactive Intestinal Peptide) is a synthetic 28-residue peptide supplied for controlled laboratory research, analytical evaluation, and in-vitro experimentation. This 6mg research format is provided as a lyophilized powder with lot-specific quality documentation.
Laboratory studies involving VIP commonly focus on its molecular identity, receptor-binding characteristics, VPAC1 and VPAC2 receptor systems, ligand-receptor selectivity, second-messenger measurements, and related biochemical signaling variables. These applications are limited to appropriately designed research systems and should not be interpreted as evidence of clinical utility or suitability for use in humans or animals.
VIP (6mg) – Research Specifications:
| Product Name |
VIP |
| Full Name |
Vasoactive Intestinal Peptide |
| Content |
6mg per vial |
| Peptide Length |
28 amino-acid residues |
| Reference Sequence |
HSDAVFTDNYTRLRKQMAVKKYLNSILN-NH2 |
| Reference Molecular Formula |
C147H237N43O43S |
| Reference Molecular Weight |
Approximately 3325.8 g/mol |
| Reference CAS Number |
40077-57-4 |
| Form |
Lyophilized powder |
| Purity and Identity |
Refer to the lot-specific Certificate of Analysis |
| Analytical Documentation |
Lot-specific testing documentation is available |
| Storage Conditions |
Store sealed and protected from heat, light, and moisture according to the applicable COA and validated laboratory SOPs. |
| Research Classification |
For laboratory research use only |
| Excluded Uses |
Not for human or animal consumption or for clinical, diagnostic, therapeutic, veterinary, food, cosmetic, or supplement use. |
Reference identifiers and calculated properties may vary according to peptide form, counterion, salt content, and analytical convention. The lot-specific Certificate of Analysis governs the material supplied.
What Is VIP? Research Background and Mechanistic Context
VIP is an endogenous peptide sequence first characterized through biochemical isolation and analytical research. Synthetic VIP is used as a reference material in controlled studies examining peptide structure, molecular recognition, receptor interactions, and associated signaling measurements.
VIP is principally associated with the VPAC1 and VPAC2 receptor families. Depending on the study design, researchers may use the peptide to examine ligand-binding affinity, receptor selectivity, concentration-dependent assay responses, second-messenger activity, or comparative behavior across experimental systems.
Research conclusions depend on the model, assay conditions, controls, analytical method, and material characterization. Results obtained in isolated cells, receptor assays, biochemical systems, or other laboratory models cannot be directly extrapolated to human or animal outcomes.
Important Research Notice: Lot-specific Certificates of Analysis are available to document reported identity, purity, and analytical results. Researchers should confirm that the applicable documentation satisfies their internal quality requirements before use.
THIS PRODUCT IS INTENDED EXCLUSIVELY FOR LABORATORY RESEARCH. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT INTENDED FOR CLINICAL, DIAGNOSTIC, THERAPEUTIC, VETERINARY, FOOD, COSMETIC, OR SUPPLEMENT APPLICATIONS.
VIP (6mg) – Key Research Applications
1. Peptide Identity and Analytical Characterization
VIP may be used as a reference material in analytical workflows examining peptide identity, chromatographic behavior, mass characteristics, stability variables, and method performance. Study parameters should be documented in accordance with the laboratory’s validated procedures.
2. VPAC Receptor-Binding Research
Controlled in-vitro systems may use VIP to investigate binding behavior involving VPAC1 or VPAC2 receptors. Common experimental variables include receptor expression, ligand concentration, incubation conditions, comparator compounds, and assay-specific response measurements.
3. Second-Messenger and Signal-Transduction Assays
VIP may be evaluated in laboratory assays designed to measure receptor-associated molecular events and downstream second-messenger activity. Experimental interpretation requires appropriate negative controls, positive controls, predefined endpoints, and validated analytical methods.
4. Comparative Ligand and Receptor Studies
Researchers may include VIP in comparative studies involving related peptide ligands, receptor subtypes, analogs, or assay platforms. Consistent material handling, lot tracking, and standardized experimental conditions are necessary when comparing results across runs or cohorts.
Handling and Research Use Considerations
VIP should be handled only by qualified laboratory personnel in appropriately equipped facilities. Laboratories should maintain documentation for receipt, storage, preparation, experimental use, and disposal.
Before beginning an experiment, researchers should verify:
- Product identity and lot number
- Container and label integrity
- Lot-specific Certificate of Analysis availability
- Applicable storage requirements
- Suitability of the material for the validated research method
- Required controls and analytical endpoints
- Institutional and regulatory requirements
Environmental conditions, assay design, sample preparation, instrumentation, and operator technique can affect experimental results. Laboratories should use consistent procedures and document deviations that may influence data interpretation.
This information is provided solely for laboratory product identification and research documentation. It does not provide dosing, administration, clinical-use, veterinary-use, or consumer-use guidance.
VIP (6mg) – Certificate of Analysis (COA)
Lot-specific Certificates of Analysis are available for VIP (6mg). The applicable COA contains the analytical information reported for the tested lot and may include identity, purity, test methods, and related quality parameters.
Researchers should match the vial lot number to the corresponding COA and retain the documentation within the laboratory’s quality-management records.
Where to Buy VIP (6mg) for Research Purposes
NordSci supplies VIP (6mg) exclusively for controlled laboratory research, analytical evaluation, and in-vitro experimentation. Procurement teams should verify product labeling, lot traceability, analytical documentation, storage requirements, and alignment with institutional purchasing policies before ordering.
IMPORTANT: VIP is not a drug, dietary supplement, food, cosmetic, or medical product. It is not approved or supplied for human or animal consumption or for clinical, diagnostic, therapeutic, or veterinary applications. No dosing, administration, or application guidance is provided.
Scientific References
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Said SI, Mutt V. Polypeptide with broad biological activity: isolation from small intestine. Science. 1970;169(3951):1217–1218.
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Harmar AJ, Fahrenkrug J, Gozes I, et al. Pharmacology and functions of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacological Reviews. 2012;64(2):293–344.
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International Union of Basic and Clinical Pharmacology. VPAC1 and VPAC2 receptor nomenclature and pharmacology resources.
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UniProt Consortium. VIP_HUMAN: vasoactive intestinal peptide precursor, accession P01282.
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Lot-specific NordSci Certificate of Analysis for VIP (6mg).