Thymosin Alpha-1 (3/10mg) – Product Description
Thymosin Alpha-1 is a synthetic peptide research material corresponding to a defined 28-amino-acid sequence. It is supplied as a lyophilized powder in 3mg and 10mg vial sizes for laboratory research, analytical characterization, and controlled in vitro experimentation.
Research applications may include peptide identity testing, molecular-interaction analysis, cell-based assay development, receptor-associated measurements, cytokine-associated marker analysis, and gene-expression testing. References to thymic-derived or immune-cell-derived laboratory systems describe experimental models and measurable endpoints only.
Results obtained from these systems do not establish safety, effectiveness, clinical utility, or an effect on human or animal physiology.
Thymosin Alpha-1 (3/10mg) – Research Specifications:
| Compound |
Thymosin Alpha-1 (Tα1) |
| Unit Size |
3mg or 10mg per vial |
| Unit Quantity |
1 vial |
| Sequence |
Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn-OH |
| Molecular Formula |
C129H215N33O55 |
| Molecular Weight |
Approximately 3108.3 g/mol |
| CAS Number |
62304-98-7 |
| Compound Type |
Synthetic peptide research material |
| Form |
Lyophilized powder |
| Source |
Chemical synthesis |
| Purity and Identity |
Refer to the applicable lot-specific Certificate of Analysis |
| Analytical Documentation |
May include HPLC, mass spectrometry, or other reported analytical results |
| Storage Conditions |
Store sealed at −20°C or below and protect from light, heat, and moisture unless otherwise stated in the applicable documentation |
| Research Classification |
Laboratory research and analytical use only |
| Restrictions |
Not for human or animal consumption or for in vivo, diagnostic, therapeutic, food, drug, cosmetic, or dietary-supplement use |
What Is Thymosin Alpha-1? Research Background and Mechanistic Context
Thymosin Alpha-1 is a synthetic 28-amino-acid peptide corresponding to a sequence originally identified during the analytical study of thymic peptide fractions. Synthetic production gives laboratories access to a defined research material suitable for controlled analytical and in vitro methods.
Laboratory research may examine Thymosin Alpha-1 in selected cellular assay systems. Researchers can establish predefined endpoints such as peptide identity, molecular binding, receptor-associated measurements, transcription-associated markers, cell-surface markers, or cytokine-associated analytes.
These measurements characterize observations within a controlled experimental system. They do not establish an effect on immunity, infection, inflammation, disease, vaccination, or any other human or animal outcome.
Experimental interpretation should account for the selected cell type, assay format, concentration range, exposure period, controls, sample-processing conditions, analytical platform, and predefined acceptance criteria. Findings should remain limited to the methods and endpoints used in the study.
Important Research Notice: Nordsci research materials include access to lot-specific analytical documentation. Consult the applicable Certificate of Analysis for reported identity, purity, and testing information.
THIS PRODUCT IS INTENDED EXCLUSIVELY FOR LABORATORY RESEARCH. NOT FOR HUMAN OR ANIMAL CONSUMPTION. NOT FOR IN VIVO, DIAGNOSTIC, THERAPEUTIC, FOOD, DRUG, COSMETIC, OR DIETARY-SUPPLEMENT USE.
Thymosin Alpha-1 – Key Research Applications
1. Immune-Cell-Derived Assay Research
Thymosin Alpha-1 may be evaluated in controlled in vitro systems containing T-cell-derived or other immune-cell-derived laboratory models. Researchers can measure predefined cellular and molecular markers under documented experimental conditions.
Any observed response remains specific to the selected model, assay method, controls, and analytical endpoints. It must not be interpreted as evidence of an effect on human or animal immune function.
2. Cytokine-Associated Marker Analysis
Laboratories may use Thymosin Alpha-1 in assays designed to measure selected cytokine-associated analytes. Study plans should define the target analytes, reference controls, sampling intervals, analytical platform, and acceptance criteria before testing begins.
A measured change in a cytokine-associated analyte does not independently demonstrate anti-inflammatory, antimicrobial, antiviral, immunostimulatory, or therapeutic activity.
3. Cell-Surface and Gene-Expression Studies
Researchers may examine selected cell-surface or gene-expression-associated markers following exposure to Thymosin Alpha-1 within a controlled in vitro model. Test conditions can be compared with untreated, vehicle, baseline, or other suitable laboratory controls.
Observed differences remain limited to the selected assay system. They do not establish clinical relevance or effects on infection, inflammation, vaccination, disease, or other human or animal outcomes.
4. Comparative Thymic-Peptide Research
Thymosin Alpha-1 may be compared with other thymic peptide research materials, including
Thymalin,
through standardized analytical or in vitro methods.
Comparative experiments can evaluate differences in peptide identity, analytical characteristics, molecular interactions, or assay-specific marker measurements. Conclusions should account for model variability, controls, testing methodology, and the limitations of the selected analytical platform.
Handling and Research Use Considerations
Thymosin Alpha-1 should be handled exclusively by qualified laboratory personnel using established procedures for synthetic peptide research materials. Laboratories should document product receipt, lot identification, storage conditions, sample allocation, analytical methods, testing results, and disposal.
This product information does not provide preparation, concentration, dosing, injection, administration, application, or in vivo instructions.
Protocol Design Considerations:
- Define the cellular model, molecular target, or analytical endpoint.
- Establish suitable positive, negative, vehicle, and baseline controls.
- Document culture conditions, temperature, timing, exposure conditions, and sample-processing variables.
- Use qualified analytical methods and predefined acceptance criteria.
- Record the product lot number and retain the associated Certificate of Analysis.
- Document instrument settings, calibration procedures, and testing conditions.
- Limit conclusions to the selected model, methods, controls, and observed results.
- Follow applicable institutional requirements for storage, handling, recordkeeping, and disposal.
Note: This information is provided exclusively as a laboratory research reference. All work must be conducted by qualified personnel in appropriately equipped facilities.
Thymosin Alpha-1 – Certificate of Analysis (COA)
Lot-specific Certificates of Analysis provide analytical information for the applicable Thymosin Alpha-1 product lot. Reported documentation may include identity, purity, analytical methodology, mass confirmation, chromatographic results, and other lot-specific findings.
Researchers should verify that the lot number printed on the product vial corresponds with the lot number shown on the applicable COA. Analytical results apply exclusively to the tested lot and do not establish clinical safety, effectiveness, regulatory approval, or suitability for human or veterinary use.
Where to Buy Thymosin Alpha-1 (3/10mg) for Research Purposes
Nordsci Peptides supplies Thymosin Alpha-1 in 3mg and 10mg vial sizes as a synthetic laboratory research material. Each product lot includes access to applicable analytical documentation through the Nordsci COA Library.
Qualified laboratories should review product identity, lot-specific analytical results, storage requirements, batch traceability, and institutional procurement standards before acquiring the material.
IMPORTANT: Thymosin Alpha-1 is sold exclusively for laboratory research and analytical use. It is not a drug, food, dietary supplement, cosmetic, or therapeutic product. It is not approved for human or veterinary use and must not be used for consumption, diagnosis, treatment, prevention, compounding, or any in vivo procedure.
Scientific References
- Goldstein AL, Low TLK, McAdoo M, et al. Thymosin alpha one: isolation and sequence analysis of an immunologically active thymic polypeptide. Proceedings of the National Academy of Sciences. 1977;74(2):725–729.
- United States Pharmacopeia. General Chapter <621>, Chromatography.
- United States Pharmacopeia. General Chapter <736>, Mass Spectrometry.
- International Council for Harmonisation. ICH Q2(R2): Validation of Analytical Procedures.
- Lot-specific Thymosin Alpha-1 Certificate of Analysis and associated analytical documentation.