PT-141 or Bremelanotide is a research peptide that is currently being studied for its potential use in treating sexual dysfunction in both men and women. It was derived from Melanotan 2, a synthetic version of a peptide hormone that naturally occurs in the body and stimulates melanogenesis. This hormone, known as alpha-Melanocyte stimulating hormone or MSH, has various effects on the body, including the stimulation of certain melanocortin receptors. PT-141 has been shown in studies to activate the melanocortin receptors MC1R and MC4R, resulting in an increase in sexual desire without affecting skin tanning.
PT-141 has demonstrated effectiveness in treating sexual dysfunction in both male and female rats, with male rats responding at lower doses than females. Melanotan 2, the peptide from which PT-141 was derived, was originally tested as a sunless tanning agent and was found to have unexpected side effects, including sexual arousal and spontaneous erections in male volunteers.
It is important to note that PT-141 is still undergoing scientific study and is not yet approved for clinical use. Therefore, any findings or observations related to its functionality, mechanics, and benefits should only be the result of studies conducted in a strictly controlled environment.
The primary concern for peptide researchers today is product purity. Nord-sci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.
THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION. ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY.
All products are produced using lyophilization (freeze-drying), a preservation method that allows peptides to remain fully stable during shipping for approximately 3-4 months. Once a peptide has been reconstituted with bacteriostatic water, it must be refrigerated to maintain integrity. After reconstitution, peptides typically remain stable for up to 30 days when stored properly.
Lyophilization, also referred to as cryodesiccation, is a specialized dehydration process in which peptides are first frozen and then exposed to a low-pressure environment. This causes the water within the vial to transition directly from a solid to a vapor (sublimation), leaving behind a dry, crystalline white material known as a lyophilized peptide. In this powdered form, peptides may be safely stored at room temperature until they are ready to be reconstituted with bacteriostatic water.
After delivery, peptides should be protected from heat and light. If use is expected within the near future (whether days, weeks, or a few months) refrigerated storage below 4°C (39°F) is generally sufficient. Lyophilized peptides are commonly stable at room temperature for several weeks or longer, making short-term ambient storage acceptable when use is anticipated within that timeframe.
For extended storage, ranging from several months to multiple years, freezing is strongly recommended. Storage at -80°C (-112°F) offers optimal long-term stability and helps preserve peptide structure and quality over time.
For more detailed guidance on peptide handling and storage best practices, please refer to the resource below:
PT-141 (also known as bremelanotide) is a research peptide investigated for its role in melanocortin receptor signaling and central arousal pathway modeling. In controlled laboratory settings, it is commonly used to study neuroendocrine mechanisms that intersect motivation, arousal signaling, and downstream behavioral endpoints. Each vial is prepared to research-grade standards and is intended to support reproducible, protocol-driven experimental design.
PT-141 Research Peptide Specifications:
| Unit Size | 10 mg/vial |
| Unit Quantity | 1 vial |
| Purity (HPLC) | > 99% |
| Identity | PT-141 (Bremelanotide), melanocortin pathway research peptide |
| Appearance | Lyophilized White Powder |
| Source | Chemical Synthesis |
| Storage Conditions | Store lyophilized PT-141 at −20 °C or below, protected from light and moisture. Reconstituted solutions should be stored at 2–8 °C and used promptly within approved research workflows, following institutional handling and documentation standards. |
| Research Use Only | This peptide is supplied exclusively for laboratory research use. Not for human consumption, clinical use, or veterinary applications. Please review all terms and conditions prior to purchase. |
PT-141 is primarily studied as a melanocortin-pathway research tool, with emphasis on central signaling rather than peripheral hormone replacement models. In preclinical literature, melanocortin receptor activity has been linked to motivational and arousal-related signaling networks, which is why PT-141 is often integrated into study designs that track behavioral metrics alongside neuroendocrine readouts.
In modern protocols, researchers frequently position PT-141 within broader experimental systems that include comparator arms or adjunct peptides used for stress gating, recovery readiness, and endocrine context. For example, pairing PT-141 with Selank may be used to evaluate how anxiety-like behavior or stress load influences approach behavior metrics in standardized arenas. In other designs, MT-2 (Melanotan II) is referenced as a related melanocortin-pathway compound when labs are mapping receptor-level similarities and differences across ligands.
Important Research Notice: Nordsci peptides are supported by independent third-party analytical testing to validate identity and purity via HPLC and mass spectrometry. A Certificate of Analysis (COA) is available for each lot to support documentation, traceability, and internal quality controls.
THIS PRODUCT IS INTENDED FOR LABORATORY RESEARCH USE ONLY. NOT FOR HUMAN CONSUMPTION. NOT INTENDED TO DIAGNOSE, TREAT, CURE, OR PREVENT ANY DISEASE OR CONDITION.
If you’re building a structured libido-pathway or arousal-signaling protocol, prioritize verified identity, clean purity, and traceable documentation to reduce assay noise and improve reproducibility across cohorts.
Shop all peptidesPT-141 is commonly used to interrogate central melanocortin-linked signaling pathways in controlled models. Research programs typically focus on how receptor engagement translates into measurable outcomes such as approach behavior, latency metrics, preference indices, and other standardized behavioral endpoints.
Behavioral models are sensitive to stress, novelty, sleep disruption, and environmental instability. PT-141 is therefore often evaluated alongside peptides used to contextualize the “noise” in arousal studies. In some frameworks, Selank or Semax are included to examine neurobehavioral modulation that may influence downstream readouts in standardized testing environments.
Many labs do not study PT-141 in isolation. Instead, it is positioned as one component in a phased protocol—single-agent baselines first, followed by combination arms where research teams can attribute signal changes with more confidence. PT-141 is frequently discussed in “libido & sexual function” research frameworks that also consider endocrine context (e.g., HCG) and recovery-readiness markers (sleep quality, stress panels, activity normalization).
Because peptides can degrade with temperature drift, repeated freeze–thaw cycles, and improper solvent selection, PT-141 protocols often emphasize strict cold-chain handling, aliquoting, and documented preparation steps. Tight process controls help preserve signal fidelity and reduce false negatives or inconsistent effect sizes across experimental runs.
Reconstitution Guidelines for Laboratory Use:
In laboratory environments, lyophilized PT-141 is typically reconstituted using bacteriostatic water or another suitable sterile diluent to achieve a target stock concentration aligned with the study’s dosing and delivery model. The final concentration, route, timing, and exposure schedule should be set by the research team based on peer-reviewed literature, model selection, and institutional approvals.
Protocol Design Considerations: For behavior-linked research, consistency is a core KPI. Standardize light/dark cycles, habituation windows, arena conditions, diet/hydration controls, and assessment timing relative to dosing to reduce confounding variables.
Note: The information above is provided as a high-level research reference only. All experimental use must be conducted by qualified personnel in appropriately equipped facilities, following applicable regulations and institutional animal care and use policies.
Each lot of PT-141 is supported by a Certificate of Analysis documenting peptide identity, purity, and analytical methods used (HPLC, mass spectrometry, and related assays as applicable). COA documentation supports protocol files, internal audits, and traceability requirements in quality-managed research environments.
Sourcing PT-141 for institutional use requires suppliers with transparent quality systems, consistent labeling, and reliable analytical documentation. When selecting a vendor, labs should validate lot identifiers, COA access, purity thresholds, and storage/shipping practices that protect peptide integrity end-to-end.
IMPORTANT: PT-141 is sold exclusively for in vitro and preclinical research applications. It is not approved for human use or any therapeutic purpose. Researchers are responsible for complying with all applicable regulations and institutional policies governing peptide research in their jurisdiction.
High-signal studies come from disciplined sourcing and handling: verified purity, documented lots, cold-chain consistency, and protocol-first experimentation.
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