MK-677 (25MG)

MK-677 is a long-acting, ghrelin receptor agonist and HGH stimulator.  It is also known as Ibutamoren, MK-677, 191, L-163, and formerly known as Oratrope. 

In one study published in Endocrinology, eight beagles were given 0.25mg/kg of MK-677 and their GH levels increased 5.3 times over the baseline (15.8). When they increased the dose to 0.5mg/kg, the GH levels increased 9 times over the baseline rates. When the dose was further increased to 1 mg/kg, the GH levels increased by almost 16 times of the baseline. It’s important to note that these doses were oral vs. injection.

Furthermore, after eight hours the insulin-like growth factor remained elevated by 30% and GH was elevated for up to six hours, indicating MK-677 is a long-acting compound in beagles. Cortisol was also elevated, however it was modest compared to the elevation of the GH levels.

MK-677 is also an orally active gherkin receptor agonist which stimulates food intake, GH secretion, and regulates reward signaling.

In addition to hunger signaling, MK-677 modulates stress, glucose, body weight, cognition, gut motility, hunger, adiposity, and even pain.

In a study published in the International Journal of Molecular Sciences, MK-677 has also been shown to increase neural activity and reduce the death of neurons and neuroinflammation.

The primary concern for SARMs researchers today is product purity.  Nordsci guarantees our product purity by performing independent testing of our products and providing those certifications for our customers in our product descriptions.

THIS PRODUCT IS NOT INTENDED TO TREAT, CURE OR DIAGNOSE ANY CONDITION OR DISEASE AND IS NOT FOR HUMAN CONSUMPTION

ALL PRODUCTS OFFERED ARE INTENDED FOR LABORATORY RESEARCH USE ONLY